structure of spleen ppt

Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The venous sinuses consist of a lining of endothelial cells that are positioned in parallel and connected by stress fibres to annular fibres, which are composed of extracellular-matrix components. It can store platelets in case of an emergency. The red blood cells can be released when needed. The spleen is encased in a thick connective-tissue capsule. 1- Cleanses the blood by removing old RBCs and platelets, as well as debris from the blood. Normal Structure, Function, and Histology of the Spleen MARK F. C ESTA Integrated Laboratory Systems, Inc., Durham, North Carolina 27713, USA ABSTRACT The spleen is the largest secondary immune organ in the body and is responsible for initiating … If you continue browsing the site, you agree to the use of cookies on this website. Since the spleen is so rich with blood flow, bleeding from a rupture can be signi… Now customize the name of a clipboard to store your clips. The spleen reaches peak development at puberty, in rats, followed by gradual involution (Losco, 1992). This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. Location and Structure of Spleen 2. If you continue browsing the site, you agree to the use of cookies on this website. Find PowerPoint Presentations and Slides using the power of XPowerPoint.com, find free presentations research about Function And Structure Of Spleen PPT Obliquely along 10 rib, directed downwards, forwards and lat. The spleen is the largest accumulation of lymphoid tissue in the body. Learn about its function, location in the body, and conditions that can affect the spleen. A component of the lymphatic system, bone marrow functions primarily to produce blood cells and to store fat.Bone marrow is highly vascular, meaning that it is richly supplied with a large number of blood vessels.There are two categories of bone marrow tissue: red marrow and yellow marrow. You can change your ad preferences anytime. It also influences antibody formation. The Thymus: Gross Specimen Thymic Structure Thymus ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3bf4ef-MTM1Z Because the red-pulp cords contain a large number of macrophages, ageing erythrocytes that are no longer able to pass through the slits are phagocytosed. • Wedge shaped. Enlargement of the spleen is treated by addressing the underlying illness. An enlarged spleen can be detected by physician examination or via diagnostic imaging. The spleen can become enlarged as a result of infection, anemia or cancer. 4-the splenophrenic, which connects the spleen to the diaphragm. Cells of reticulum do not stain deeply with carmine, and in this respect differ from the cells of the Malpighian corpuscles. C.E. In humans, up to a cup (236.5 ml) of red blood cells can be held in the spleen and released in cases of hypovolemia. Structure of the spleen. WebMD's Spleen Anatomy Page provides a detailed picture, definition, and information about the spleen. The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. Tuftsin binds to specific receptors on the surface of macrophages and polymorphonuclear leukocytes, stimulating their migration, phagocytic, bactericidal, and tumoricidal activity. 1 At presentation, the spleen is involved in up to 40% of patients with Hodgkin’s disease (HD) and non-Hodgkin’s lymphoma (NHL), and this increases to 70% at postmortem.1, 2, 3 Accurate assessment of the spleen in lymphoma is important because it can alter tumor staging, influence … , and is directed upward, backward, and to the left, except at its upper end, where it is directed slightly medially. 2- Stores the breakdown products of RBCs site of erythrocyte production in the fetus. The lymphatic system is the system of ducts and lymph nodes which are found under the skin. No public clipboards found for this slide. You can change your ad preferences anytime. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The spleen is surrounded by a capsule of dense connective tissue from which emerge trabeculae, which divide the parenchyma, or splenic pulp, into incomplete compartments.Large trabeculae originate at the hilum, on the medial surface of the spleen; these trabeculae carry nerves, arteries and veins. Similar in structure to a large lymph node, it acts primarily as a blood filter. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Some have believed the spleen to be derived from the mesenchyme of the dorsal mesentery, with or without the participation of the coelomic epithelium; s… 3-the splenocolic, which connects the spleen to the colic flexure and to the thoracic diaphragm. The splenic artery enters the spleen at the hilus, then that run through the parenchyma or pulp of the spleen. The spleen is very vascular and reddish purple in color; its size and weight vary. If you continue browsing the site, you agree to the use of cookies on this website. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. Spleen Aida1983. The spleen contains T and B lymphocytes as well as many phagocytes and is a major component of the mononuclear phagocyte system. The spleen is soft, highly vascular and dark purple in colour. • Wedge shaped 2. Spleen • Lymphatic organ connected to blood vascular system • Part of mononuclear phagocyte system. The human spleen is surrounded by a capsule of dense connective tissue containing relatively little muscle and therefore incapable of the extensive contraction exhibited by the muscular capsule of the spleen in dogs and cats. Thus, the spleen is situated between the fundus of the stomach and the diaphragm. Procedures Aida1983. The spleen is the largest single mass of lymphatic tissue in the body. • Part of mononuclear phagocyte system. The spleen is a large, encapsulated, bean-shaped organ that is situated on the left side of the body below the diaphragm. Looks like you’ve clipped this slide to already. Looks like you’ve clipped this slide to already. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Now customize the name of a clipboard to store your clips. All the efferents pass into the intestinal lymph trunks, which then enter the cisterna chyli or the abdominal confluence of lymph trunks. Presentation 11 Aida1983. See our User Agreement and Privacy Policy. The spleen is located in the upper-left part of the abdomen. The reason for this is unknown but may relate to the fact that lower blood pressure allows less rapid flow and minimizes damage to normal erythrocytes. Fractures Aida1983. of areolar plane. Structure of GB Fundus -Ant:ant.abdominal wall - Post.inf: transverscolon Body sup: liver stpost.inf: Tr.colon. Location and Structure of Spleen: Spleen lies in between the fundus of the stom­ach and the diaphragm. Up to a quarter of lymphocytes can be stored in the spleen at any one time, 1. Functions. The WP is the primary immunologic region of the spleen in both species; however, the WP makes up less than a quarter of splenic tissue. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The spleen is divided by function and structure into the red pulp (RP) and white pulp (WP); in between these two regions is the marginal zone (MZ) in rodents and the perifollicular zone in humans (1, 2). Bone marrow is the soft, flexible connective tissue within bone cavities. Schema of a venous sinus located in the cords of the red pulp. Spleen- Structure and Functions. End of 1 part of doudenum , begins of 2nd part of doudenum Neck - Form the cystic duct, 4cm Hartmann’s Pouch 1. Spleen It functions in a manner. Basic structure of the spleen Although it varies in size between individuals, a spleen is typically around 3–5.5 inches long and weighs 5.3–7.1 ounces (oz). The spleen is an organ shaped like a shoe that lies relative to the 9th and 11th ribs and is located in the left hypochondrium and partly in the epigastrium. The spleen is in the portal circulation. The spleen is delivered to the midline by means of blunt and sharp dissection of the areolar plane between the kidney and the pancreas. If you continue browsing the site, you agree to the use of cookies on this website. The spleen is an organ found in virtually all vertebrates.Similar in structure to a large lymph node, it acts primarily as a blood filter.The word spleen comes from Ancient Greek σπλήν (splḗn).. This is pain that the patient feels somewhere other than where the injury is located. Spleen is covered by a connective tissue capsule which is again enveloped by a serous membrane, the peritoneum. Dreamy249. See our Privacy Policy and User Agreement for details. The spleen is an organ found in virtually all vertebrates. spleen. The peritoneum is closely adherent to the outside of the capsule. This enlargement is a result of an excess of trapped blood cells that can damage the spleen's function. The capsule is deeply indented at the medial aspect of the organ and this indentation is known as hilus (hilum) of the spleen.
It’s protected by the rib cage. Spleen • situated principally in the left hypochondriac region, but its superior extremity extends into the epigastric region 3. The spleen plays important roles in regard to red blood cells (erythrocytes) and the immune system. The Spleen Anatomy Of Spleen White Pulp Spleen Structure The White PPT. Blood Circulation in Spleen 3. It lies just beneath the left half of the diaphragm close to the 9th, 10th, and 11th ribs.
WHERE IS THE SPLEEN LOCATED
... Thymus gland ppt. Numerous references discuss the effects of aging on lymphocyte function and changes in the distribution of lymphocyte subsets. The stress fibres run along the long axis of the endothelial cells and are most prominent where the endothelial cells are in contact. The spleen. The spleen functions as a hematopoietic center until late fetal life. The spleen is an organ located in the upper left abdomen, and is roughly the size of a clenched fist. Presentation Summary : The Spleen Anatomy of Spleen White Pulp Spleen Structure The white pulp is circular in structure and is made up mainly of lymphocytes. Functions of the spleen . With the spleen retracted medially, the phrenicocolic ligament is incised. In a trauma patient with an injury to the abdomen, the most common symptoms of a ruptured spleen are pain and tenderness of the abdomen, particularly on the left upper quadrant. Blood from the cords collects in the sinuses (shown by arrows). 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